| 发明名称 |
CO-CRYSTALS OF TRAMADOL AND NSAIDS |
| 摘要 |
The present invention relates to co-crystals of tramadol and co-crystal formers selected from NSAIDs, processes for preparation of the same and their uses as medicaments or in pharmaceutical formulations, more particularly for the treatment of pain.
In a preferred embodiment, co-crystals of (-)tramadol-(S)-naproxen (1:2) and (+)tramadol-(R)-naproxen (1:2) are prepared. |
| 申请公布号 |
KR20110069860(A) |
申请公布日期 |
2011.06.23 |
| 申请号 |
KR20117010637 |
申请日期 |
2009.10.16 |
| 申请人 |
LABORATORIOS DEL DR. ESTEVE, S.A. |
发明人 |
BUSCHMANN HELMUT HEINRICH;SOLA CARANDELL LLUIS;BENET BUCHHOLZ JORDI;CERON BERTRAN JORDI CARLES;PLATA SALAMAN CARLOS RAMON;TESSON NICOLAS |
| 分类号 |
A61K31/135;A61K31/192;A61P29/00;C07C217/74 |
主分类号 |
A61K31/135 |
| 代理机构 |
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