发明名称 IMPROVED DOSING REGIMEN OF TEMOZOLOMIDE FOR TREATMENT OF CANCER BASED ON MGMT LEVEL OF PATIENT
摘要 <p><P>PROBLEM TO BE SOLVED: To provide a new method and a kit for the treatment of a subject suffering from proliferative disorders such as a cancer, a tumor or a metastatic disease. <P>SOLUTION: The use of temozolomide for the manufacture of a medicament to treat cancer in a patient requiring treatment is disclosed, which includes an administration of temozolomide according to the improved dosing regimen and/or administration schedule based on the MGMT level of the patient. In addition, a further improved dosing regimen and/or administration schedule for the treatment of patient with temozolomide are/is disclosed. <P>COPYRIGHT: (C)2011,JPO&INPIT</p>
申请公布号 JP2011121960(A) 申请公布日期 2011.06.23
申请号 JP20110003480 申请日期 2011.01.11
申请人 SCHERING CORP 发明人 ZONG CHEN;WINOGRAD BENJAMIN
分类号 A61K31/4188;A61K45/00;A61P35/00;A61P35/04;A61P43/00;C12Q1/48;G01N33/50;G01N33/574 主分类号 A61K31/4188
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