发明名称 |
USE OF A NEUROFILAMENT PEPTIDE FOR THE TREATMENT OF GLIOMA |
摘要 |
The present invention provides a new drug to treat malignant glioma, which is the most prevalent type of primary tumor of the central nervous system (CNS). The present invention indeed shows that the isolated NFL-TBS40-63 peptide is highly specific for glioma cells, in which it triggers apoptosis. It is therefore presented here for use in a method for treating malignant glioma. The present invention further relates to the use of the NFL-TBS40-63 peptide for detecting specifically glioma cells either in vivo, or in vitro, or for addressing chemical compounds to said tumor cells. |
申请公布号 |
CA2784091(A1) |
申请公布日期 |
2011.06.23 |
申请号 |
CA20102784091 |
申请日期 |
2010.12.14 |
申请人 |
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM);THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING / MCGILL UNIVERSIT Y;UNIVERSITE D'ANGERS |
发明人 |
EYER, JOEL;PETERSON, ALAN;BALZEAU, JULIEN;BERGES, RAPHAEL |
分类号 |
A61K38/16;A61P25/00;A61P35/00 |
主分类号 |
A61K38/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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