发明名称 USE OF A NEUROFILAMENT PEPTIDE FOR THE TREATMENT OF GLIOMA
摘要 The present invention provides a new drug to treat malignant glioma, which is the most prevalent type of primary tumor of the central nervous system (CNS). The present invention indeed shows that the isolated NFL-TBS40-63 peptide is highly specific for glioma cells, in which it triggers apoptosis. It is therefore presented here for use in a method for treating malignant glioma. The present invention further relates to the use of the NFL-TBS40-63 peptide for detecting specifically glioma cells either in vivo, or in vitro, or for addressing chemical compounds to said tumor cells.
申请公布号 CA2784091(A1) 申请公布日期 2011.06.23
申请号 CA20102784091 申请日期 2010.12.14
申请人 INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM);THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING / MCGILL UNIVERSIT Y;UNIVERSITE D'ANGERS 发明人 EYER, JOEL;PETERSON, ALAN;BALZEAU, JULIEN;BERGES, RAPHAEL
分类号 A61K38/16;A61P25/00;A61P35/00 主分类号 A61K38/16
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