发明名称 VINYL SULPHONE FUNCTIONALISED LIPID SYSTEMS. SYNTHESIS AND USES
摘要 Vinyl sulphone functionalised lipid systems. Synthesis and uses. Compound comprising a molecule of lipid nature and a vinyl sulphone group permitting the realisation of lipidation of biomolecules in a highly efficacious and simple manner. The present invention furthermore relates to procedures of the obtainment thereof and uses thereof. More particularly, it relates to the use of such compounds in the development of two new applications of ISCOMs based on nanoencapsulation capacity and incorporation of antibodies into the membrane thereof: a) employment thereof in fluorescent immunolabelling; b) development of systems for the directed transport of drugs.
申请公布号 WO2011073473(A1) 申请公布日期 2011.06.23
申请号 WO2010ES00525 申请日期 2010.12.15
申请人 UNIVERSIDAD DE GRANADA;SANTOYO GONZALEZ, FRANCISCO;OSUNA CARRILLO DE ALBORNOZ, ANTONIO;MORALES SANFRUTOS, JULIA;MEGIA FERNANDEZ, ALICIA;CRUZ BUSTOS, TERESA;GONZALEZ GONZALEZ, GLORIA MARIBEL 发明人 SANTOYO GONZALEZ, FRANCISCO;OSUNA CARRILLO DE ALBORNOZ, ANTONIO;MORALES SANFRUTOS, JULIA;MEGIA FERNANDEZ, ALICIA;CRUZ BUSTOS, TERESA;GONZALEZ GONZALEZ, GLORIA MARIBEL
分类号 C07C317/08;A61K31/10;A61K39/39;A61K47/48;B82B1/00;C07C315/04;C07C317/18;C07C317/38 主分类号 C07C317/08
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