| 发明名称 |
BETA-CELL REPLICATION PROMOTING COMPOUNDS AND METHODS OF THEIR USE |
| 摘要 |
In the invention provides for a method of stimulating or increasing ß-cell replication or growth, by contacting a ß-cell with an inhibitor of adenosine kinase (ADK), an inhibitor of S-Adenosylhomocysteine hydrolase (SAHH) or an activator of AMP activated protein kinase (AMPK).
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| 申请公布号 |
CA2784596(A1) |
申请公布日期 |
2011.06.23 |
| 申请号 |
CA20102784596 |
申请日期 |
2010.12.17 |
| 申请人 |
JOSLIN DIABETES CENTER, INC.;THE BRIGHAM AND WOMEN'S HOSPITAL, INC.;PRESIDENT AND FELLOWS OF HARVARD COLLEGE |
发明人 |
ANNES, JUSTIN P.;MELTON, DOUGLAS A.;RUBIN, LEE L.;WEIR, GORDON |
| 分类号 |
C12N5/071;A61K31/7042;A61K35/39;A61P3/10;C12N5/02 |
主分类号 |
C12N5/071 |
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