Recombinant production of heparin binding proteins
摘要
<p>A process for recovering and purifying refolded heparin binding proteins produced in heterologous host cells includes the step of incubation of the solubilized protein with a polyanionic species such as dextran sulfate.</p>
申请公布号
EP2336164(A1)
申请公布日期
2011.06.22
申请号
EP20100192270
申请日期
2006.12.19
申请人
GENENTECH, INC.
发明人
BUTLER, MICHELLE D.;CLELAND, JEFFREY L.;KAHN, DAVID W.;PIZARRO, SHELLY;SCHMELZER, CHARLES H.;WINKLER, MARJORIE E.