COMPOSITION AND METHOD FOR TREATMENT OF PRETERM LABOR
摘要
<p>The invention provides a method for treating or preventing preterm labor in pregnant female subjects. The method comprises the step of administering a therapeutically effective amount of a Toll-like Receptor 9 antagonist sufficient to prevent the activation of Toll-like Receptor 9 by fetal DNA. The invention further provides compositions comprising a Toll-like Receptor 9 antagonist for use in the methods of the invention. The compositions and methods of the present invention enhance gestation and therefore improve neonatal morbidity and mortality.</p>
申请公布号
EP2334300(A2)
申请公布日期
2011.06.22
申请号
EP20090783381
申请日期
2009.09.24
申请人
THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN;THE COOMBE LYING-IN HOSPITAL
发明人
O'NEILL, LUKE ANTHONY;O'LEARY, JOHN;DALY, SEAN;SCHARFE NUGENT, ANDREA