发明名称 |
Protein formulations for use at elevated temperatures |
摘要 |
Liquid formulations of bone morphogenetic proteins are provided for prolonged use at elevated temperatures. More specifically, the invention relates to liquid formulations comprising rhGDF-5, trehalose, and one or more biocompatible excipients that provide stability to the protein for at least 30 days at temperatures up to body temperature.
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申请公布号 |
US7964561(B2) |
申请公布日期 |
2011.06.21 |
申请号 |
US20100695357 |
申请日期 |
2010.01.28 |
申请人 |
ADVANCED TECHNOLOGIES AND REGENERATIVE MEDICINE, LLC |
发明人 |
GARIGAPATI VENKATA;SU DONGLING;LOPEZ JULIUS |
分类号 |
A61K38/16;A61K38/17;A61K38/18;C07H1/00 |
主分类号 |
A61K38/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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