| 发明名称 |
RAF INHIBITORS AND THEIR USES. |
| 摘要 |
<p>The present invention provides imidazooxazole and imidazothiazole compounds and their syntheses. The compounds of the present invention are capable of inhibiting the activity of RAF kinase, such as B-RAF<sup> V600E</sup>. The compounds are useful for the treatment of cell proliferative disorders such as cancer.</p> |
| 申请公布号 |
MX2011005788(A) |
申请公布日期 |
2011.06.21 |
| 申请号 |
MX20110005788 |
申请日期 |
2009.12.04 |
| 申请人 |
ARQULE, INC. |
发明人 |
LIU, YANBIN;ASHWELL, MARK A.;LAPIERRE, JEAN-MARC;TANDON, MANISH |
| 分类号 |
C07D498/04;A61K31/424;A61K31/429;A61P35/00;C07D513/04 |
主分类号 |
C07D498/04 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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