发明名称 |
Method of identifying a potential substrates of an O-methyltransferase |
摘要 |
The invention provides crystalline O-methyltransferases and isolated non-native O-methyltransferases as well as sets of their structural coordinates. Also provided are methods of predicting the activity or substrate specificity of putative O-methyl-transferases, methods of identifying potential substrates of O-methyltransferases, and methods of identifying potential inhibitors of methyltransferases.
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申请公布号 |
US7966133(B2) |
申请公布日期 |
2011.06.21 |
申请号 |
US20080135950 |
申请日期 |
2008.06.09 |
申请人 |
THE SALK INSTITUTE FOR BIOLOGICAL STUDIES;THE SAMUEL ROBERTS NOBLE FOUNDATION |
发明人 |
NOEL JOSEPH P.;ZUBIETA CHLOE;DIXON RICHARD |
分类号 |
G01N31/00;C12N9/10;C12Q1/48;G01N33/48;G06F19/00;G06G7/58 |
主分类号 |
G01N31/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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