发明名称 |
Buprenorphine derivatives and uses thereof |
摘要 |
Ester derivatives of the phenolic hydroxyl group of buprenorphine can be used in the treatment of opiate dependency and/or moderate to severe pain. The esters have an enhanced bioavailability, an enhanced duration of action, and a reduced abuse potential.
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申请公布号 |
US7964610(B2) |
申请公布日期 |
2011.06.21 |
申请号 |
US20070294462 |
申请日期 |
2007.03.27 |
申请人 |
RECKITT BENCKISER HEALTHCARE (UK) LIMITED |
发明人 |
LEWIS JOHN WILLIAM;CHAPLEO CHRISTOPHER BOURNE |
分类号 |
A61K31/4748;C07D491/08 |
主分类号 |
A61K31/4748 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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