发明名称 Imidazole derivatives
摘要 The present invention relates to imidazole derivatives of formula I wherein R1, R2, R3, R4, X, Y and R are described hereinabove, or a pharmaceutically acceptable salt thereof. The invention also relates to a pharmaceutical composition comprising the imidazole derivatives of formula I, a process for preparing a compound of formula I, and a method of treating or preventing acute and/or chronic neurological disorder comprising administering to a patient in need of such treatment and/or prevention a therapeutically effective amount of said pharmaceutical composition. These disorders include Alzheimer's disease. These disorders also include mild cognitive impairment.
申请公布号 US7964620(B2) 申请公布日期 2011.06.21
申请号 US20080211849 申请日期 2008.09.17
申请人 HOFFMANN-LA ROCHE INC. 发明人 BUETTELMANN BERND;CECCARELLI SIMONA MARIA;JAESCHKE GEORG;KOLCZEWSKI SABINE;PORTER RICHARD HUGH PHILIP;VIEIRA ERIC
分类号 A61K31/4439;A61K31/4164;C07D233/64;C07D401/06;C07D401/14 主分类号 A61K31/4439
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