发明名称 |
POROUS COMPOSITE CHITOSAN-GELATIN MATRIX FOR BONE DEFECT FILLING |
摘要 |
FIELD: medicine. ^ SUBSTANCE: invention refers to medicine and concerns composites for waxed reconstruction of the injured bone tissues. High-porous elastic chitosan-gelatin matrixes of porosity 90 % or more consist of chitosan and contain gelatin up to 60 wt % and sodium lauryl sulphate up to 0.2-0.4 wt %. The porous structure is produced by introducing the additives, freezing and sublimation drying. ^ EFFECT: due to elasticity and high porosity, said sponges fill bone defects with a minimum clearance that promotes the uniform formation of bone tissue throughout the defect; high solubility of matrixes provides fast bone tissue genesis. ^ 1 tbl, 1 ex |
申请公布号 |
RU2421229(C1) |
申请公布日期 |
2011.06.20 |
申请号 |
RU20100114768 |
申请日期 |
2010.04.14 |
申请人 |
UCHREZHDENIE ROSSIJSKOJ AKADEMII NAUK INSTITUT METALLURGII I MATERIALOVEDENIJA IM. A.A. BAJKOVA RAN;ROSSIJSKAJA FEDERATSIJA, OT IMENI KOTOROJ VYSTUPAET MINISTERSTVO OBRAZOVANIJA I NAUKI ROSSIJSKOJ FEDERATSII |
发明人 |
BARINOV SERGEJ MIRONOVICH;SMIRNOV VALERIJ VJACHESLAVOVICH;FEDOTOV ALEKSANDR JUR'EVICH;KOMLEV VLADIMIR SERGEEVICH;FADEEVA INNA VILOROVNA;TJUT'KOVA JULIJA BORISOVNA |
分类号 |
A61K31/722;A61K33/06;A61L27/12;A61L27/26;A61L27/56 |
主分类号 |
A61K31/722 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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