发明名称 NOVEL SPIRO[IMIDAZOLIDINE-4,3'-INDOLE]-2,2',5(1'H)-TRIONES FOR TREATING CONDITIONS ASSOCIATED WITH VANILLOID RECEPTOR 1
摘要 FIELD: chemistry. ^ SUBSTANCE: invention relates to a compound (4R)-1'-[(2E)-3-(3,4-dichlorophenyl)prop-2-en-1-yl]-2H,5H-spiro[imidazolidine-4,3'-indole]-2,2',5(1'H)-trione or pharmaceutically acceptable salt thereof. The invention also relates to use of the said compound to prepare a medicinal agent for use in therapy of conditions associated with vanilloid receptor 1 (VR1). ^ EFFECT: novel optical isomer which can be used to treat acute or chronic disorders. ^ 6 cl, 2 tbl
申请公布号 RU2421457(C2) 申请公布日期 2011.06.20
申请号 RU20080131905 申请日期 2007.02.06
申请人 ASTRAZENEKA AB 发明人 L'JUNG KARMEN;TOMASHEVSKI MIROSLAV;VU SAJMON
分类号 A61K31/4188;A61P25/02;C07D487/10 主分类号 A61K31/4188
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