Lægemiddel til behandling af HIV-inficerede pattedyr
摘要
The present invention provides an assay for determining the biochemical fitness of a biochemical species in a mutant replicating biological entity relative to its predecessor. The present invention further provides a continuous fluorogenic assay for measuring the anti-HIV protease activity of protease inhibitor. The present invention also provides a method of administering a therapeutic compound that reduces the chances of the emergence of drug resistance in therapy.
申请公布号
DK1088098(T3)
申请公布日期
2011.06.20
申请号
DK19990931861T
申请日期
1999.06.23
申请人
THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES;THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
发明人
GULNIK, SERGEI, V.;ERICKSON, JOHN, W.;MITSUYA, HIROAKI;GOSH, ARUN K.