发明名称 |
Pharmaceutical Composition Comprising Cinchonains Ia And Ib, Process For Preparing An Epimeric Mixture Of Cinchonains Ia And Ib, Use And Method For Reverting/Combating Ventricular Fibrillation |
摘要 |
The present invention relates to the effects of the epimeric mixture of cinchonains Ia and Ib on pathologies that involve alterations in the cardiovascular system, essentially in combating, preventing and reverting ventricular fibrillation in human beings and animals, especially for combating spontaneous or electric-stimulus-induced ventricular fibrillation, to revert spontaneous or electric-stimulus-induced ventricular fibrillations, for preventing ventricular fibrillation, for the treatment of ventricular fibrillation of any etiology or for the treatment of post-fibrillation to maintain normal cardiac rhythm. The present invention further relates to methods for the synthesis of an epimeric mixture of the chemical substances cinchonain Ia and Ib. The present invention also relates to the use of these chemical substances in reverting/combating ventricular fibrillation and/or in protecting against ventricular fibrillation. A pharmaceutical composition will be used for administering these chemical substances in human beings and animals.
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申请公布号 |
US2011144193(A1) |
申请公布日期 |
2011.06.16 |
申请号 |
US20100947263 |
申请日期 |
2010.11.16 |
申请人 |
LABORATORIO CATARINENSE S/A |
发明人 |
SILVA FILHO NEY OSVALDO;VELASCO IRINEU TADEU;NETO AUGUSTO SCALABRINI;PIANOWSKI LUIZ |
分类号 |
A61K31/35;A61P9/00;C07D493/04 |
主分类号 |
A61K31/35 |
代理机构 |
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地址 |
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