| 摘要 |
The present invention relates to time-temperature indicator (TTI) systems comprising indolenin based spiropyrans containing a N-acetylamido or N-acetylester side chain, especially to a time temperature indicator comprising at least one spiropyran indicator of formula (I) Wherein R1 is hydrogen,—C1-C18 alkoxy,—C1-C18 alkylthio,—C1-C18 alkyl-SO—,—C1-C18 alkyl-SO2—, phenylthio, phenyl, halogen,—C1-C18 alkylthio,—C1-C18 alkyl-SO—,—C1-C18 alkyl-SO2—, phenylthio, phenyl, halogen,—C1-C18 alkyl or—NO2; R2 is hydrogen or—C1-C18 alkoxy; R3 is NO2 or halogen; R4 is hydrogen,—C1-C18 alkoxy or halogen; R5 is hydrogen, halogen,—C1-C18 alkoxy,—COOH,—COO—C1-C18alkyl,—CF3 or phenyl; R6 is hydrogen or R6 and R7 form together a phenyl ring; R7 is hydrogen; Ra is hydrogen or—C1-C6 alkyl; Rb is hydrogen or—C1-C6 alkyl, or together with Ra form a 5-6 membered ring; Y is—CH2—COO—R8 or—CH2—CO—N(R10)—R9; or CH2—CO—N(R10)-L-N(R10) CO—CH2—or Y is—CH2—CO—O-L′-O—CO—CH2—wherein R8 is hydrogen, C3-C18alkyl or R8 is ethyl with the proviso that R6 and R7 form together a phenyl ring; R9 is phenyl, mesityl, phenyl-O-phenyl, phenyl-S-phenyl, phenyl once or more than once substituted by halogen,—CF3, C1-C6alkyl,—C1-C6 alkoxy, carboxy,—COO—C1-C6alkyl whereby in case of a more than once substitution, the substituent can be the same or different; R10 is hydrogen, C1-C18alkyl; L is 1,3 phenylene or 1,4 phenylene wherein the phenylene linker is optionally substituted by once or more than once by halogen,—CF3, C1-C18 alkoxy, carboxy,—COO—C1-C18alkyl,—CONH2,—CON(C1-C18alkyl)2, nitro; or L is naphthalene, biphenylene or phenylene-O-phenylene wherein the naphthalene, biphenylene or phenylene-O-phenylene linker is optionally substituted once or more than once by halogen,—CF3, C1-C18alkyl,—C1-C18 alkoxy, carboxy,—COO—C1-C18alkyl,—CONH2,—CON(C1-C18alkyl)2, nitro; L′is 1,3 phenylene
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