The present invention is directed to a topical formulation comprising (a) an NSAID or a pharmaceutically acceptable salt thereof; (b) a polyhydric alcohol; (c) a C10 - C14 straight chain fatty acid at derivative thereof; (d) a C2 - C4 alcohol; (e) a gelling agent selected from the group consisting of non-ionic polymers; (f) optionally additional pharmaceutically acceptable excipients; and (g) water up to 100 %. The topical formulation has improved skin penetration properties.
申请公布号
WO2011070318(A2)
申请公布日期
2011.06.16
申请号
WO2010GB02240
申请日期
2010.12.06
申请人
RECKITT BENCKISER HEALTHCARE INTERNATIONAL LIMITED;KIRKWOOD, ANDREW;DAVIS, ADRIAN