发明名称 |
5-AMINO- 4-HYDROXYPENTOYL AMIDES |
摘要 |
HIV inhibitors of formula (I) wherein R1 is halo, C1-4alkoxy, trifluoromethoxy; R2 is a group of formula (A); R3 is a group of formula (B); R4 is a group of formula (C); n is 0 or 1; A is CH or N; R5 and R6 are hydrogen, C1-4alkyl, halo; R7 and R8 are C1-4alkyl or C1-4alkoxyC1-4alkyl; R9 is C1-4alkyl, cyclopropyl, trifluoromethyl, C1-4alkoxy, or dimethylamino; R10 is hydrogen, C1-4alkyl, cyclopropyl, trifluoromethyl, C1-4alkoxy, or dimethylamino; pharmaceutically acceptable addition salts and solvates thereof; pharmaceutical compositions containing these compounds as active ingredient and processes for preparing said compounds.
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申请公布号 |
CA2783929(A1) |
申请公布日期 |
2011.06.16 |
申请号 |
CA20102783929 |
申请日期 |
2010.12.10 |
申请人 |
JANSSEN R&D IRELAND;MEDIVIR AB |
发明人 |
KALAYANOV, GENADIY;KESTELEYN, BART RUDOLF ROMANIE;PARKES, KEVIN;SAMUELSSON, BENGT BERTIL;SCHEPENS, WIM BERT GRIET;THURING, JOHANNES WILHELMUS J.;WALLBERG, HANS KRISTIAN;WEGNER, JOERG KURT |
分类号 |
C07D213/64;A61K31/506;A61P31/18;C07D213/74;C07D277/30;C07D401/12;C07D405/12;C07D417/12;C07D493/04 |
主分类号 |
C07D213/64 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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