发明名称 |
FRIZZLED-BINDING AGENTS AND USES THEREOF |
摘要 |
Novel anti-cancer agents, including, but not limited to, antibodies, that bind to human frizzled receptors are provided. Novel epitopes within the human frizzled receptors which are suitable as targets for anti-cancer agents are also identified. Methods of using the agents or antibodies, such as methods of using the agents or antibodies to inhibit Wnt signaling and/or inhibit tumor growth are further provided. |
申请公布号 |
KR20110066189(A) |
申请公布日期 |
2011.06.16 |
申请号 |
KR20117009364 |
申请日期 |
2009.09.28 |
申请人 |
ONCOMED PHARMACEUTICALS, INC. |
发明人 |
GURNEY AUSTIN L.;SATO AARON KEN;AXELROD FUMIKO TAKADA;HOEY TIMOTHY CHARLES;SATYAL SANJEEV H.;MITRA SATYAJIT SUJIT KUMAR |
分类号 |
C07K16/18;A61K39/395;A61P35/00 |
主分类号 |
C07K16/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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