| 发明名称 |
N-SUBSTITUTED DEOXYNOJIRIMYCIN COMPOUNDS FOR USE IN INHIBITING OSTEOCLASTOGENESIS AND/OR OSTEOCLAST ACTIVATION |
| 摘要 |
Agents, which are both ceramide glucosyltransferase inhibitors and glucosidase inhibitors, may inhibit osteoclastogenesis and/or reduce osteoclast activation and, therefore, may be useful for osteolytic activity and bone loss in subjects with conditions, such as multiple myeloma.
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| 申请公布号 |
CA2783405(A1) |
申请公布日期 |
2011.06.16 |
| 申请号 |
CA20102783405 |
申请日期 |
2010.07.30 |
| 申请人 |
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD |
发明人 |
KARADIMITRIS, ANASTASIOS;HORWOOD, NIKKI;RAHEMTULLA, AMIN;DELL, ANNE;BUTTERS, TERRY;DWEK, RAYMOND |
| 分类号 |
A61K31/445;A61P19/00 |
主分类号 |
A61K31/445 |
| 代理机构 |
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