发明名称 |
ARYL ALKYL CARBOXYLIC ACID SALTS, PROCESS FOR PREPARATION AND DOSAGE FORMS |
摘要 |
The invention particularly discloses a process for preparing aryl alkyl carboxylic acid salts by preparing aqueous alkali solution, adding aryl alkyl carboxylic acid to said alkali solution at a temperature ranging from 4° to 121° C. for obtaining a clear solution, preferably by heating and/or stirring and concentrating and cooling to obtain aryl alkyl carboxylic acid salt The invention therefore discloses solid oral dosage forms and compositions of aryl alkyl carboxylic acid salts which are free of organic solvent/so. The solid oral dose compositions of aryl alkyl carboxylic acid salts of the invention are prepared in situ from aryl alkyl carboxylic acids and bases to obtain aryl acid alkyl carboxylic acid sails in crystalline/powder form with or without the use of pharmaceutical excipients.
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申请公布号 |
US2011144207(A1) |
申请公布日期 |
2011.06.16 |
申请号 |
US200913058978 |
申请日期 |
2009.08.14 |
申请人 |
SHASUN CHEMICALS AND DRUGS LIMITED |
发明人 |
CHODANKAR NANDKUMAR;BIYANI MILIND;MUTHUNARAYANAN MOHAN;RADHAKRISHNAN SELVARAJU;SANTHANAMPILLAI SATHISH KUMAR;NADAR RAJENDRAN PAUL;SUNDARAMURTHY VIVEKANANDAN;PRABU SAKTHIVEL LAKSHAMANA |
分类号 |
A61K31/19;A61P29/00;C07C59/185;C07C63/00;C07C63/04;C07C63/33;C07C65/24;C07C229/40;C07D209/26;C07D491/052 |
主分类号 |
A61K31/19 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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