| 发明名称 |
PHENYL-ALKYL PIPERAZINES HAVING TNF-MODULATING ACTIVITY, PREPARATION METHOD, AND THERAPEUTIC USE THEREOF |
| 摘要 |
The present invention relates to phenyl-alkyl piperazines of formula (I): in which A, R1, R2 and R3 are as defined herein, having TNF-modulating activity. The invention also relates to the preparation thereof, pharmaceutical compositions thereof, and to the therapeutic use thereof.
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| 申请公布号 |
US2011144120(A1) |
申请公布日期 |
2011.06.16 |
| 申请号 |
US20100970047 |
申请日期 |
2010.12.16 |
| 申请人 |
SANOFI-AVENTIS |
发明人 |
BARONI MARCO;RITZELER OLAF;ZANCHET MARCO |
| 分类号 |
A61K31/496;A61K31/495;A61P19/02;A61P29/00;C07D241/04;C07D401/04 |
主分类号 |
A61K31/496 |
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