<p>The present invention provides methods of treating a ß-arrestin2 mediated and/or GPR120 mediated response in a subject. The ß-arrestin2 mediated and/or GPR120 mediated response can be inflammation, including diabetes, inflammation associated with obesity and obesity. The methods can comprise administering to a subject a therapeutically effective amount of a compound predicted to bind a ß-arrestin2 molecule and/or GPR120, wherein the compound selectively activates a ß-arrestin2-dependent signaling pathway of GPR120.</p>
申请公布号
WO2011072132(A1)
申请公布日期
2011.06.16
申请号
WO2010US59699
申请日期
2010.12.09
申请人
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;OLEFSKY, JERROLD, M.;OH, DA, YOUNG