| 发明名称 |
LINEARES, SCHWERES ANTIKÖRPERKETTENFRAGMENT VH- CH1-VH-CH1 |
| 摘要 |
The invention provides an antibody which comprises a linear V H -C H 1-V H -C H 1 heavy chain fragment associated with two light chain fragments, wherein the C-terminus of C H 1 is joined directly to the N-terminus of V H at the Fd-Fd junction of the heavy chain fragment, a nucleic acid encoding the heavy chain fragment, and a method for the preparation of said antibody. |
| 申请公布号 |
AT510854(T) |
申请公布日期 |
2011.06.15 |
| 申请号 |
AT20060022818T |
申请日期 |
1996.04.05 |
| 申请人 |
GENENTECH, INC. |
发明人 |
RINDERKNECHT, ERNST H.;ZAPATA, GERARDO A. |
| 分类号 |
C07K16/00;C12N15/09;A61K38/00;A61K39/395;A61P37/02;C07K1/20;C07K16/06;C07K16/28;C07K16/32;C07K16/44;C07K16/46;C12N15/13;C12P21/04;C12P21/08 |
主分类号 |
C07K16/00 |
| 代理机构 |
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代理人 |
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