发明名称 IN VITRO METHOD FOR PROGNOSIS OR PREDICTION OF RESPONSE BY PATIENTS WITH RHEUMATOID ARTHRITIS TO TREATMENT WITH TNF-alpha FACTOR BLOCKING AGENTS
摘要 In vitro method and kit for prognosis or prediction of the response of rheumatoid arthritis patients to treatment with TNF-± factor blocking agents, which comprises determining, in a blood sample from said patients, the expression level of at least one of the eight genes selected from the group: HLA-DRB3, EAT2, GNLY, CAMP, SLC2A3, IL2RB, MXD4 and TLR5 or combinations thereof and comparing said expression level to the expression values obtained from responsive and non-responsive patients who showed responsiveness to the treatment and those who showed non-responsiveness thereto.
申请公布号 EP2333110(A1) 申请公布日期 2011.06.15
申请号 EP20090815707 申请日期 2009.09.18
申请人 FUNDACIO INSTITUT DE RECERCA DE L'HOSPITAL UNIVERSITARI VALL D'HEBRON 发明人 JULIA CANO, ANTONIO;MARSAL BARRIL, SARA
分类号 C12Q1/68 主分类号 C12Q1/68
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