发明名称 |
ANTI-APRIL MONOKLONALER ANTIKÖRPER UND DEREN VERWENDUNG ZUR BEHANDLUNG VON IMMUNERKRANKUNGEN ODER KREBS |
摘要 |
<p>Methods of using one or more agonists to modulate activity of he members of the TNF and TNFR families referred to as TALL-1, APRIL, TACI, and BCMA are provided. The methods include in vitro, in situ , and/or in vivo diagnosis and/or treatment of mammalian cells or pathological conditions associated with TALL-1, APRIL, TACI, or BCMA, using one or more agonist or antagonist molecules. The methods of treatment disclosed by the invention include methods or treating immune related diseases and cancer.</p> |
申请公布号 |
AT511857(T) |
申请公布日期 |
2011.06.15 |
申请号 |
AT20050025025T |
申请日期 |
2000.11.28 |
申请人 |
GENENTECH, INC. |
发明人 |
ASHKENAZI, AVI;DODGE, KELLY;GREWAL, IQBAL;KIM, KYUNG;MARSTERS, SCOT;PITTI, ROBERT;YAN, MINHONG |
分类号 |
A61K39/395;C12N15/09;A61K38/00;A61K45/00;A61K47/48;A61P25/00;A61P29/00;A61P35/00;A61P35/02;A61P37/00;A61P37/06;A61P43/00;C07K14/52;C07K14/525;C07K14/705;C07K16/28;C07K16/46;C12N5/10;C12P21/08 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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