发明名称 5-MEMBERED HETEROCYCLIC COMPOUND
摘要 Provided is a compound having a superior acid secretion suppressive action, which shows an antiulcer activity and the like. A compound represented by the formula (I) or a salt thereof: wherein ring A is a saturated or unsaturated 5-membered heterocycle containing, as a ring-constituting atom besides carbon atoms, at least one heteroatom selected from a nitrogen atom, an oxygen atom and a sulfur atom, the ring-constituting atoms X 1 and X 2 are the same or different and each is C or N, the ring-constituting atoms X 3 and X 4 are the same or different and each is C, N, O or S (provided that a pyrrole ring wherein X 1 is N is excluded from ring A), and when the ring-constituting atom X 3 or X 4 is C or N, each ring-constituting atom optionally has substituent(s) selected from an optionally substituted alkyl, an acyl, an optionally substituted hydroxy, an optionally substituted mercapto, an optionally substituted amino, a halogen, a cyano and a nitro; R 1 and R 2 are each a cyclic group optionally having substituent(s); R 3 and R 4 are each H or alkyl, or R 3 and R 4 form, together with the adjacent N, an nitrogen-containing heterocycle; and Y is a spacer.
申请公布号 EP2196459(A4) 申请公布日期 2011.06.15
申请号 EP20080833168 申请日期 2008.09.24
申请人 TAKEDA PHARMACEUTICAL COMPANY LIMITED 发明人 NISHIDA, HARUYUKI;ARIKAWA, YASUYOSHI;HIRASE, KEIZO
分类号 C07D233/64;A61K31/381;A61K31/4164;A61K31/426;A61K31/506;A61P1/00;A61P1/04;A61P35/00;A61P43/00;C07D233/68;C07D277/28;C07D333/20;C07D333/22;C07D403/04 主分类号 C07D233/64
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