COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF MUTANT EGFR GENE
摘要
The invention relates to combinations of a double-stranded ribonucleic acid (dsRNA) targeting a mutant Epidermal Growth Factor Receptor (EGFR), and a double-stranded ribonucleic acid (dsRNA) targeting interleukin-6 (IL-6), and their use in treating cancer.
申请公布号
EP2331690(A1)
申请公布日期
2011.06.15
申请号
EP20090792177
申请日期
2009.09.02
申请人
ALNYLAM PHARMACEUTICALS INC.;ALNYLAM EUROPE AG.;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
发明人
SAH, DINAH;TAN, PAMELA;PEREZ, MARIA DEL MAR INDA;FURNARI, FRANK;CAVENEE, WEBSTER;BONAVIA, RUDY