发明名称 |
PYRIDYL NON-AROMATIC NITROGENATED HETEROCYCLIC-1-CARBOXYLATE ESTER DERIVATIVE |
摘要 |
<p>[Problem] To provide a compound usable for treatment of diseases associated with fatty acid amide hydrolase (FAAH), especially for treatment of urinary frequency and urinary incontinence, overactive bladder and/or pain. [Means for Solution] We have found that a novel pyridyl non-aromatic nitrogen-containing heterocyclic-1-carboxylate derivative and its pharmaceutically acceptable salt has a potent FAAH-inhibitory activity. Further, the pyridyl non-aromatic nitrogen-containing heterocyclic-1-carboxylate derivative of the present invention has an excellent effect for increasing an effective bladder capacity, an excellent effect for relieving urinary frequency and an excellent anti-allodynia effect, and is therefore usable for treatment of urinary frequency and urinary incontinence, overactive bladder and/or pain.</p> |
申请公布号 |
EP1849773(A4) |
申请公布日期 |
2011.06.15 |
申请号 |
EP20060713839 |
申请日期 |
2006.02.16 |
申请人 |
ASTELLAS PHARMA INC. |
发明人 |
ISHII, TAKAHIRO;SUGANE, TAKASHI;MAEDA, JUN;NARAZAKI, FUMIE;KAKEFUDA, AKIO;SATO, KENTARO;TAKAHASHI, TATSUHISA;KANAYAMA, TAKATOSHI;SAITOH, CHIKASHI;SUZUKI, JOTARO;KANAI, CHISATO |
分类号 |
C07D213/65;A61K31/44;A61K31/4545;A61K31/4709;C07D213/80;C07D213/82;C07D401/12;C07D401/14;C07D405/14;C07D413/12;C07D413/14;C07D417/14 |
主分类号 |
C07D213/65 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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