发明名称 |
5-[2-(METHYLTHIO)ETHOXY] AND PYRIMIDINE-2-AMINE MANUFACTURING METHOD |
摘要 |
<p>A novel method for preparing 5-[2-(methylthio)ethoxylpyrimidin-2-amine useful as a regent or raw material for manufacture of medicaments, agricultural chemicals, and industrial products, which comprises alkanoylating the amino group of a 2-amino-4-alkoxypyrimidine, then converting the resultant into a 4-hydroxypyrimidine compound by a treatment with anhydrous aluminum chloride, further etherifying the 4-hydroxypyrimidine compound by a reaction with a 2-haloethyl methyl sulfide in the presence of a base, and removing the alkanoyl group to obtain 5-[2-(methylthio)ethoxylpyrimidin-2-amine.</p> |
申请公布号 |
EP2332923(A1) |
申请公布日期 |
2011.06.15 |
申请号 |
EP20090812905 |
申请日期 |
2009.09.11 |
申请人 |
KOWA COMPANY, LTD. |
发明人 |
YAMAZAKI, KOICHI;KUSAKABE, TAICHI;OHGIYA, TADAAKI;SHIBUYA, KIMIYUKI |
分类号 |
C07D239/47;C07D401/12;C07D471/04 |
主分类号 |
C07D239/47 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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