| 发明名称 |
Bivalent Smac mimetics and the uses thereof |
| 摘要 |
The invention relates to bivalent mimetics of Smac which function as inhibitors of Inhibitor of Apoptosis Proteins. The invention also relates to the use of these mimetics for inducing apoptotic cell death and for sensitizing cells to inducers of apoptosis.
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| 申请公布号 |
US7960372(B2) |
申请公布日期 |
2011.06.14 |
| 申请号 |
US20070800220 |
申请日期 |
2007.05.04 |
| 申请人 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN |
发明人 |
WANG SHAOMENG;SUN HAIYING;QIN DONGGUANG;NIKOLOVSKA-COLESKA ZANETA;LU JIANFENG;QIU SU;PENG YUEFENG;CAI QIAN |
| 分类号 |
A61K31/545;C07D225/00;C07D403/00 |
主分类号 |
A61K31/545 |
| 代理机构 |
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代理人 |
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