发明名称 HETEROCYCLIC AMIDE DERIVATIVES AS CYTOKINE INHIBITORS
摘要 Disclosed are amide compounds of formula (I) wherein Ar1, Q, Y and R3-R6 of formula (I) are defined herein. The compounds inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. Also disclosed are processes for preparing these compounds and pharmaceutical compositions comprising these compounds.
申请公布号 CA2478232(C) 申请公布日期 2011.06.14
申请号 CA20032478232 申请日期 2003.04.10
申请人 BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. 发明人 GAO, DONGHONG AMY;GOLDBERG, DANIEL R.;HAMMACH, ABDELHAKIM;HAO, MING-HONG;MOSS, NEIL;QIAN, KEVIN CHUNGENG;ROTH, GREGORY PAUL;SARKO, CHRISTOPHER RONALD;SWINAMER, ALAN DAVID;XIONG, ZHAOMING;KAMHI, VICTOR MARC
分类号 C07D333/70;A61K31/343;A61K31/381;A61K31/404;A61K31/433;A61K31/4436;A61K31/4439;A61K31/496;A61K31/497;A61K31/498;A61K31/506;A61K31/5377;A61P29/00;A61P43/00;C07C311/08;C07D209/42;C07D307/85;C07D401/12;C07D403/12;C07D409/12;C07D417/12 主分类号 C07D333/70
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