发明名称 |
THERMOSTABLE MUTANTS OF PYRROLOQUINOLINE QUINONE DEPENDENT GLUCOSE DEHYDROGENASE |
摘要 |
The present invention relates to a mutant protein of PQQ-dependent s-GDH characterized in that in at least one of the positions 122 and 124 the amino acid lysine is present, wherein these positions correspond to the amino acid positions known from the A. calcoaceticus s-GDH wild-type sequence (SEQ ID NO: 2), it also discloses genes encoding such mutant s-GDH, and different applications of these sGDH mutants, particularly for determining the concentration of glucose in a sample.
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申请公布号 |
CA2581226(C) |
申请公布日期 |
2011.06.14 |
申请号 |
CA20052581226 |
申请日期 |
2005.10.14 |
申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
BOENITZ-DULAT, MARA;KRATZSCH, PETER;SCHMUCK, RAINER |
分类号 |
C12N9/04;C12N15/53;C12Q1/32 |
主分类号 |
C12N9/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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