发明名称 Method and apparatus for determination of bone fracture risk using raman spectroscopy
摘要 A method is disclosed for analyzing keratinized tissue, particularly fingernails, of a subject to diagnose osteoporosis and bone fracture risk. A Raman spectrum of a sample of keratinized tissue is generated. Broad spectral background features of the spectrum are removed, preferably by using Fourier transform analysis. Peak heights of Raman features of interest, particularly the S—S bond of cystine, are measured. These peak height measurements are normalized using reference peak heights of Raman features that are invariant between normal and osteoporotic subjects, such as the CH2 bending peak.
申请公布号 US7962199(B2) 申请公布日期 2011.06.14
申请号 US20060994246 申请日期 2006.06.29
申请人 UNIVERSITY OF WYOMING 发明人 CARRON KEITH;TOWLER MARK
分类号 A61B5/05 主分类号 A61B5/05
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