摘要 |
FIELD: medicine. ^ SUBSTANCE: offered is a vaccine containing dimerethylenimine inactivated goose parvovirus antigen of Goosa Parvovirus Strain, VGNKI No.71, clone 6 of the activity not less 6.5-7.5 lg "ö"50/cm3 mixed with the oil adjuvant Montanide ISA-70, taken in the ratio 1:1-1:4; the dimerethylenimine concentration is not less than 0.1%. A method of goose parvovirus infection vaccination includes the intramuscular introduction of the vaccine preparation to a bird of a parental flock in a single dose 2.5104-2.5105 ""50/cm3 30 days prior to the expected oviposition. ^ EFFECT: vaccine preparation is harmless for the birds, exhibits the evident antigenic and immunogenic activity, invokes an intense long immune response in geese for the entire reproductive period; the single application of the inactivated preparation is more technological and saving, reduces immune system stresses and loads in the birds. ^ 2 cl, 2 tbl, 2 ex |