发明名称 |
SCREENING METHODS OF AGENTS FOR REGULATING THE MIRNAS AND THEIR TARGETS WHICH CONTROL INSULIN SIGNALING PATHWAY |
摘要 |
PURPOSE: A method for screening a material regulating the function of USH or FOG2 which is miR-8 or miR-200 miRNA is provided. CONSTITUTION: A method for screening a material regulating insulin signal transduction comprises: a step of treating a test compound to a cell line which expresses miR-200 family miRNA or miR-8 miRNA; a step of measuring expression level or activity of FOG2 or USH protein in the cells; and a step of screening a test compound which changes the expression or activation of FOG2 or USH protein. |
申请公布号 |
KR20110061863(A) |
申请公布日期 |
2011.06.10 |
申请号 |
KR20090118393 |
申请日期 |
2009.12.02 |
申请人 |
SNU R&DB FOUNDATION |
发明人 |
KIM, VIC NARRY;LEE, JUNG HYUN;HYUN, SEO GANG;JIN HUA |
分类号 |
G01N33/68;C12N5/10;C12N15/11;G01N33/15 |
主分类号 |
G01N33/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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