发明名称 APPLICATION OF HDAC INHIBITORS FOR TREATING MYELOMA
摘要 FIELD: medicine, pharmaceutics. ^ SUBSTANCE: claimed is application of inhibitor of hystondeacetylase (HDAL) N-hydroxy-3-[4-[[[2-(2-methyl-1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2E-2-propene amide for production of medication for treating myeloma and corresponding method of treatment. ^ EFFECT: claimed substance demonstrates activity with respect to cell lines of myeloma in very low nanomolecular range, from 50 nM in contrast to earlier known HDAC inhibitors. ^ 7 cl
申请公布号 RU2420279(C2) 申请公布日期 2011.06.10
申请号 RU20080107871 申请日期 2006.08.01
申请人 NOVARTIS AG 发明人 ATADZHA PITER U.
分类号 A61K31/4045;A61K31/495;A61K45/00;A61P35/00 主分类号 A61K31/4045
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