发明名称 |
Preparation of platinum (II) complexes |
摘要 |
This invention relates a method for the preparation of platinum(II) oxalato complexes from their dihalogenoplatinum(II) precursors having either neutral monodentate or bidentate non-leaving co-ligands. Of particular interest is oxaliplatin. The method includes the step of reacting a halogenoplatinum(II) complex containing a neutral monodentate or bidentate ligand with an oxalate in a non-aqueous solvent or a mixed solvent system. The mixed solvent system is solvent mixture containing a non-aqueous solvent and water. According to the present invention, the non-aqueous solvent is an alcohol.
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申请公布号 |
US7956208(B2) |
申请公布日期 |
2011.06.07 |
申请号 |
US20070162745 |
申请日期 |
2007.01.30 |
申请人 |
PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED |
发明人 |
DU PREEZ JAN GYSBERT HERMANUS |
分类号 |
C07F15/00 |
主分类号 |
C07F15/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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