| 摘要 |
Disclosed is a method for producing medical dressing made of skin, comprising the following steps: separating, peeling and obtaining the entire thickness of skin from a pig for medical use; dipping the thus-obtained skin into low-concentration glycerol, and spin-culturing the skin using high-concentration glycerol; washing the skin using a sterile saline solution after being cultured in the high-concentration glycerol; spin-culturing the skin in a 0.1 N NaOH solution after washing; neutralizing the skin treated with the NaOH solution, in 0.1 N HCl, and washing the skin using a saline solution; cutting the washed skin, permitting the skin to have a mesh structure, and packing the skin in 20 to 30% glycerol; and placing dry ice around the packed product, and sterilizing the packed product using gamma rays. The skin dressing of the present invention employs a physical treatment method and a chemical treatment method at the same time, thus completely removing contaminants caused by pig hair and immunogens which might remain in the pig skin even after the treatment using the high-concentration glycerol. According to the present invention, the skin which is cultured in high-concentration glycerol is dipped in the low-concentration glycerol during the packing step, freeze-stored and sterilized using gamma rays, thus preventing deformation of the skin, which might occur in the event of gamma ray sterilization performed in high-concentration glycerol, and also preventing discoloration of glycerol. |
