Methods of modulating mobilization of cells from the bone marrow are provided. In a specific embodiment there is provided a method of increasing mobilization of hematopoietic precursors from the bone marrow to the peripheral blood in a subject in need thereof, the method comprising: (a) administering to the subject an agent which downregulates an activity or expression of a coagulation factor or an effector thereof; and (b) harvesting the hematopoietic precursors from the peripheral blood.
申请公布号
WO2011030332(A3)
申请公布日期
2011.06.03
申请号
WO2010IL00726
申请日期
2010.09.05
申请人
YEDA RESEARCH AND DEVELOPMENT CO. LTD.;TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES LTD.;ARONOVICH, ANNA;TCHORSH-YUTSIS, DALIT;RECHAVI, GIDEON;REISNER, YAIR