摘要 |
This invention provides compositions and methods for detecting differences in copy number of a target polynucleotide. In some cases, the methods and compositions provided herein are useful for diagnosis of fetal genetic abnormalities, when the starting sample is maternal tissue (e.g., blood, plasma). The methods and materials described apply techniques for allowing detection of small, but statistically significant, differences in polynucleotide copy number. |
申请人 |
QUANTALIFE, INC.;HINDSON, BENJAMIN;SAXONOV, SERGE;BELGRADER, PHILIP;NESS, KEVIN;LUCERO, MICHAEL;COLSTON, BILLY |
发明人 |
HINDSON, BENJAMIN;SAXONOV, SERGE;BELGRADER, PHILIP;NESS, KEVIN;LUCERO, MICHAEL;COLSTON, BILLY |