The identification of a host receptor for TDM/TDB provides useful information associated with the designing of a vaccine adjuvant. Thus, disclosed is a method for screening for an adjuvant that enables the effective vaccination against tuberculosis or other infectious diseases and cancer, which utilizes a synthetic Mincle ligand. Specifically disclosed is a method for screening for a mycobacterial glycolipid TDM or synthetic TDM as an adjuvant, which is characterized in that the screening is carried out using Mincle as an adjuvant receptor for a mycobacterial glycolipid TDM or synthetic TDM.
申请公布号
WO2011065029(A1)
申请公布日期
2011.06.03
申请号
WO2010JP06988
申请日期
2010.11.30
申请人
KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION;YAMASAKI, SHO;ISHIKAWA, ERI;ISHIKAWA, TETSUAKI;TOYONAGA, KENJI