METHOD FOR PRODUCING METHYL-{4,6-DIAMINO-2-[1-(2-FLUOROBENZYL)-1H-PYRAZOLO[3,4-B]PYRIDINO-3-YL]PYRIMIDINO-5-YL} CARBAMATE AND ITS PURIFICATION FOR USE THEREOF AS PHARMACEUTICAL SUBSTANCE

摘要

The invention relates to a method for producing methyl-{4,6-diamino-2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridino-3-yl]pyrimidino-5-yl} carbamate, i.e. the compound of formula (I), and to a method for purifying the crude product of formula (I) for use as pharmaceutically active substance. For purification, methyl-{4,6-diamino-2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridino-3-yl]pyrimidino-5-yl}carbamate-sulfinyldimethane (1:2) of formula (II) is isolated as an intermediate or is produced as an intermediate in said purification method, optionally present in a mixture.