发明名称 |
Methods for designing and preparing vaccines comprising directed sequence polymer compositions via the directed expansion of epitopes |
摘要 |
The instant invention comprises a process of preparing a composition comprising directed sequence polymer (DSP) mixtures that act as epitopes and useful as vaccines, such DSP synthesized according to a set of rules regarding the identity and the frequency of occurrence of amino acids that substitute a base or native amino acid of a known epitope. The resulting composition is a mixture of related peptides for therapeutic use as a vaccine, preferably for infectious agents that are immune evasive.
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申请公布号 |
US2011129497(A1) |
申请公布日期 |
2011.06.02 |
申请号 |
US20080288345 |
申请日期 |
2008.10.16 |
申请人 |
PEPTIMMUNE, INC. |
发明人 |
BONNIN DUSTAN;ZANELLI ERIC;KRIEGER JEFF;MATHERS THOMAS |
分类号 |
A61K39/145;A61K39/00;A61K39/02;A61K39/12;A61P31/04;A61P31/12;A61P31/16;A61P33/00;A61P37/04;C07K1/107 |
主分类号 |
A61K39/145 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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