发明名称 |
DECORATING HYDROXYAPATITE BIOMATERIALS WITH MODULAR BIOLOGICALLY ACTIVE MOLECULES |
摘要 |
A modular peptide design strategy wherein the modular peptide has two functional units separated by a spacer portion is disclosed. More particularly, the design strategy combines a hydroxyapatite-binding portion and a biomolecule-derived portion. The modular peptides have improved non-covalent binding to the surface of the HA-based materials, and are capable of initiating osteogenesis, angiogenesis, and/or osteogenic differentiation.
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申请公布号 |
US2011129611(A1) |
申请公布日期 |
2011.06.02 |
申请号 |
US20090628666 |
申请日期 |
2009.12.01 |
申请人 |
WISCONSIN ALUMNI RESEARCH FOUNDATION |
发明人 |
MURPHY WILLIAM L.;LEE JAE SUNG;MARKEL MARK D.;GRAF BEN K. |
分类号 |
B05D1/28;B05D1/18;C07K2/00;C07K5/10;C07K7/06;C07K7/08;C07K14/00 |
主分类号 |
B05D1/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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