发明名称 Phthalazine Derivatives with Angiogenesis Inhibiting Activity
摘要 The invention relates to new phthalazine derivatives of formula I, and to processes for the preparation thereof, the application thereof in a process for the treatment of the human or animal body, the use thereof alone or in combination with one or more other pharmaceutically active compounds for the treatment especially of a disease that responds to the inhibition of especially the vascular endothelial growth factor receptor kinase, preferably the treatment of a proliferative disease, or the treatment of inflammatory rheumatic or rheumatoid arthritis and/or pain; and the use of such a compound alone or in combination with one or more other pharmaceutically active compounds for the manufacture of a pharmaceutical preparation for the treatment of said diseases in an animal.
申请公布号 US2011130399(A1) 申请公布日期 2011.06.02
申请号 US20100953837 申请日期 2010.11.24
申请人 NOVARTIS AG 发明人 BOLD GUIDO;MANLEY PAUL WILLIAM
分类号 A61K31/5377;A61K31/502;A61K31/5355;A61P19/02;A61P25/02;A61P27/02;A61P29/00;A61P35/00;A61P43/00;C07D401/06;C07D401/14;C07D405/12;C07D405/14;C07D409/12;C07D409/14;C07D413/14 主分类号 A61K31/5377
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