| 发明名称 |
THIAZOLE DERIVATIVE HAVING CB1-ANTAGONISTIC, AGONISTIC OR PARTIAL AGONISTIC ACTIVITY |
| 摘要 |
PROBLEM TO BE SOLVED: To provide a thiazole derivative which is a powerful cannabinoid (CB<SB>1</SB>) receptor antagonist, a powerful cannabinoid (CB<SB>1</SB>) receptor agonist or a powerful cannabinoid (CB<SB>1</SB>) receptor partial agonist and exhibits benefits for treating psychiatric disorders, neurological disorders, and other diseases relating to cannabinoid CB<SB>1</SB>neurotransmission. SOLUTION: The thiazole derivative is represented by formula (1), wherein R is a halogen atom and each of R<SB>1</SB>to R<SB>4</SB>is a specified substituent. COPYRIGHT: (C)2011,JPO&INPIT
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| 申请公布号 |
JP2011105734(A) |
申请公布日期 |
2011.06.02 |
| 申请号 |
JP20110003135 |
申请日期 |
2011.01.11 |
| 申请人 |
ABBOTT HEALTHCARE PRODUCTS BV |
发明人 |
LANGE JOSEPHUS H M;KRUSE CORNELIS G;HERREMANS ARNOLDUS H J;VAN STUIVENBERG HERMAN H;DIJKSMAN JESSICA A R;MCCREARY ANDREW C |
| 分类号 |
C07D277/20;A61K31/425;A61K31/426;A61K31/427;A61K31/454;A61K31/5377;A61K31/55;A61P1/00;A61P1/04;A61P1/08;A61P1/12;A61P1/14;A61P3/04;A61P3/10;A61P7/00;A61P9/00;A61P9/10;A61P11/00;A61P11/06;A61P11/08;A61P25/00;A61P25/02;A61P25/04;A61P25/08;A61P25/14;A61P25/16;A61P25/18;A61P25/22;A61P25/24;A61P25/28;A61P25/30;A61P25/36;A61P27/02;A61P27/06;A61P31/04;A61P31/12;A61P35/00;A61P39/02;A61P41/00;A61P43/00;C07D277/56;C07D277/68;C07D417/12 |
主分类号 |
C07D277/20 |
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