发明名称 5-LIPOXYGENASE-ACTIVATING PROTEIN (FLAP) INHIBITOR
摘要 PROBLEM TO BE SOLVED: To provide compounds and pharmaceutical compositions containing such compounds, which modulate the activity of 5-lipoxygenase-activating protein (FLAP), and also to provide methods of using such FLAP modulators, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other leukotriene-dependent or leukotriene-mediated conditions or diseases. SOLUTION: There are provided pharmaceutical compositions containing the compounds represented by chemical formula 1 (wherein each symbol is defined in specification) or salts thereof acceptable as medical drugs, or solvates acceptable as medical drugs, and excipients acceptable as medical drugs. COPYRIGHT: (C)2011,JPO&INPIT
申请公布号 JP2011105752(A) 申请公布日期 2011.06.02
申请号 JP20110015870 申请日期 2011.01.28
申请人 AMIRA PHARMACEUTICALS INC 发明人 HUTCHINSON JOHN H;PRASIT PETPIBOON PEPPI;MORAN MARK;EVANS JILLIAN F;STEARNS BRIAN ANDREW;ROPPE JEFFREY ROGER;LI YIWEI;ZUNIC JASMINE ELEANOR;ARRUDA JEANNIE M;STOCK NICHOLAS SIMON;HADDACH MUSTAPHA
分类号 C07D401/10;A61K31/404;A61K31/427;A61K31/428;A61K31/4439;A61K31/444;A61K31/4709;A61K31/497;A61K31/501;A61K31/506;A61P9/00;A61P11/00;A61P11/02;A61P11/06;A61P19/02;A61P25/00;A61P25/02;A61P25/04;A61P29/00;A61P37/08;C07D401/14;C07D403/12;C07D413/14;C07D417/14;C07D471/04 主分类号 C07D401/10
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