发明名称 |
COMPLEMENT FACTOR H-BASED ASSAYS FOR SERUM BACTERICIDAL ACTIVITY AGAINST NEISSERIA MENINGITIDIS |
摘要 |
<p>Assays for detection of bactericidal anti-Neisserial antibodies using a factor H polypeptide having a human amino acid sequence that mediates binding to Neisserial factor H binding protein (fHBp) are provided, as well as non-human animal models of Neisserial infection.</p> |
申请公布号 |
EP2326726(A1) |
申请公布日期 |
2011.06.01 |
申请号 |
EP20090812053 |
申请日期 |
2009.08.26 |
申请人 |
CHILDREN'S HOSPITAL & RESEARCH CENTER AT OAKLAND;THE UNIVERSITY OF MASSACHUSSETTS;NOVARTIS VACCINES&DIAGNOSTICS, INC. |
发明人 |
GRANOFF, DAN M.;WELSCH, JO ANNE;RAM, SANJAY |
分类号 |
C12Q1/02;A01K67/027;G01N33/68 |
主分类号 |
C12Q1/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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